Fripnit Plus 300 mg, 300 mg Tablet
PDF Leaflet Revision Date: 02 May 2023
Clinical Summary
Quick overview from the medicine insert
Indication
Prevention of active tuberculosis in high-risk patients with latent tuberculosis infection.
Dosage (summary)
Once-weekly for 12 weeks; adults: rifapentine max 900 mg, isoniazid max 900 mg.
Special Populations
- Elderly
- Hepatic impairment
- Renal impairment
Pregnancy & Breastfeeding
Not recommended during pregnancy; safety in lactation not established.
Key Drug Interactions
- Antiretroviral medicines
- Hormonal contraceptives
- Antacids
Contraindications
- Hypersensitivity
- Severe renal failure
- Acute liver disease
- Alcoholism
Common side effects
- Hypersensitivity
- Nausea
- Hepatitis
- Headache
Counselling Points
- Take with food
- Avoid tyramine-rich foods
- Report signs of hypersensitivity
Serious warnings
- Hepatotoxicity
- Severe skin reactions
- Monitor liver function
Important Disclaimer
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