Grantryl 1 mg/1 ml & 3 mg/3 ml Injection

Grantryl 1 mg/1 ml & 3 mg/3 ml Injection

S4
PDF Leaflet Revision Date: 28 November 2022

API: Granisetron | Company: Acino Pharma

Clinical Summary

Quick overview from the medicine insert

Indication

Management of nausea and vomiting induced by chemotherapy, radiotherapy, and post-operative.

Dosage (summary)

Adults: 1-3 mg IV prior to chemotherapy/radiotherapy; max 9 mg/24h. PONV: 1 mg IV prior to anesthesia.

Special Populations

  • Elderly
  • Renal impairment
  • Hepatic impairment

Pregnancy & Breastfeeding

Contraindicated during pregnancy and lactation.

Key Drug Interactions

  • Phenobarbital may increase clearance
  • Co-administer with benzodiazepines and neuroleptics

Contraindications

  • Hypersensitivity
  • Children under 2 years
  • Congenital long QT syndrome

Common side effects

  • Headache
  • Dizziness
  • Somnolence
  • Abdominal pain
  • Constipation

Counselling Points

  • Avoid driving if somnolence occurs
  • Report any signs of myocardial ischemia

Serious warnings

  • May cause dysrhythmias
  • Monitor for myocardial ischemia
  • Max 9 mg/24h
Important Disclaimer

The Grantryl 1 mg/1 ml & 3 mg/3 ml Injection professional information leaflet below is the property of Acino Pharma and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>

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