Gravtell 0,5 Mg; 1 Mg; 5 Mg 0,5 mg; 1 mg; 5 mg Hard Gelatin Capsule
PDF Leaflet Revision Date: 09 October 2024
Clinical Summary
Quick overview from the medicine insert
Indication
Primary immunosuppression in liver and kidney allograft recipients.
Dosage (summary)
Initial oral dose: 0.10-0.20 mg/kg/day for liver; 0.15-0.40 mg/kg/day for kidney, in two divided doses.
Special Populations
- Liver impairment
- Elderly patients
- Paediatric patients
Pregnancy & Breastfeeding
Contraindicated in pregnancy and breastfeeding.
Key Drug Interactions
- Ciclosporin
- Grapefruit juice
- CYP3A4 inhibitors/inducers
Contraindications
- Hypersensitivity to tacrolimus
- Pregnancy
- Lactation
- Concomitant use with live vaccines
Common side effects
- Infections
- Neoplasms
- Hyperglycaemia
- Tremor
- Headache
Counselling Points
- Take on an empty stomach
- Monitor for signs of infection
- Avoid grapefruit juice
Serious warnings
- Risk of graft rejection with formulation changes
- Increased risk of infections
- Potential for QT prolongation
Important Disclaimer
The Gravtell 0,5 Mg; 1 Mg; 5 Mg 0,5 mg; 1 mg; 5 mg Hard Gelatin Capsule professional information leaflet below is the property of Austell Pharmaceuticals and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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