Inozi-Co 300mg Tablet

    Inozi-Co 300mg Tablet

    S4
    PDF Leaflet Revision Date: 12 August 2012


    Clinical Summary

    Quick overview from the medicine insert

    Indication

    Prevention of active tuberculosis in high-risk adults and children.

    Dosage (summary)

    Adults/children u226512 years: 900 mg once weekly for 12 weeks; Children 2-11 years: weight-based dosing up to 900 mg.

    Special Populations

    • Elderly
    • Hepatic impairment
    • Renal impairment

    Pregnancy & Breastfeeding

    Not recommended during pregnancy; contraindicated in breastfeeding.

    Key Drug Interactions

    • Protease inhibitors
    • NNRTIs
    • Hormonal contraceptives

    Contraindications

    • Hypersensitivity to isoniazid/rifapentine
    • Acute/chronic liver disease
    • Severe renal failure
    • Alcoholism
    • Seizure disorders

    Common side effects

    • Nausea
    • Headache
    • Fatigue
    • Skin reactions

    Counselling Points

    • Take with food
    • Adhere to treatment regimen
    • Monitor for liver function
    • Avoid alcohol

    Serious warnings

    • Hepatotoxicity
    • Hypersensitivity reactions
    • Severe cutaneous adverse reactions
    Important Disclaimer

    The Inozi-Co 300mg Tablet professional information leaflet below is the property of Macleods Pharmaceuticals Sa and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>

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