Klacid P125 & P250 125mg / 5ml. 250mg / 5ml Granules

Klacid P125 & P250 125mg / 5ml. 250mg / 5ml Granules

S4
PDF Leaflet Revision Date: 7 July 2006

API: Clarithromycin | Company: Abbott

Clinical Summary

Quick overview from the medicine insert

Indication

Treatment of infections due to susceptible organisms.

Dosage (summary)

Children: 7.5 mg/kg twice daily; max 500 mg twice daily.

Onset of Action / Duration

Onset: 2.5 hours, Duration: 3.2 hours

Special Populations

  • Renal impairment
  • Hepatic impairment

Pregnancy & Breastfeeding

Safety not established; excreted in breast milk.

Key Drug Interactions

  • Warfarin
  • Colchicine
  • CYP3A substrates

Contraindications

  • Hypersensitivity to macrolides
  • Concomitant use with terfenadine

Common side effects

  • Diarrhoea
  • Vomiting
  • Abdominal pain
  • Rash

Counselling Points

  • Take with or without food
  • Monitor for signs of toxicity
  • Avoid in severe renal impairment

Serious warnings

  • Pseudomembranous colitis
  • Colchicine toxicity
  • QT prolongation

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Klacid P125 & P250 125mg / 5ml. 250mg / 5ml Granules
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