Lanograv. Telatri 144.5 mg FC tablet.
PDF Leaflet Revision Date: 06 February 2025
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of HIV-1 infection in adults aged 18 years and older.
Dosage (summary)
One tablet orally once daily, without regard to food.
Special Populations
- Renal impairment
- Hepatic impairment
Pregnancy & Breastfeeding
Use during pregnancy may increase risk of neural tube defects; not recommended for breastfeeding.
Key Drug Interactions
- Rifampicin decreases dolutegravir levels
- Metformin contraindicated
Contraindications
- Hypersensitivity to components
- Renal impairment
- Concomitant use with adefovir dipivoxil
- Moderate and severe hepatic impairment
Common side effects
- Nausea
- Diarrhoea
- Fatigue
- Rash
- Headache
Counselling Points
- Monitor for signs of lactic acidosis
- Avoid breastfeeding
- Use effective contraception in women of childbearing potential
Serious warnings
- Lactic acidosis
- Severe hepatomegaly
- Risk of opportunistic infections
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