Lenisolone Tablets 5 mg Tablets
PDF Leaflet Revision Date: 21 November 2023
Clinical Summary
Quick overview from the medicine insert
Indication
Corticosteroid therapy for various conditions.
Dosage (summary)
Adults: Up to 60 mg daily in divided doses; gradual withdrawal recommended.
Special Populations
- Elderly
- Paediatric population
Pregnancy & Breastfeeding
Use in pregnancy may cause fetal abnormalities; caution in breastfeeding due to potential adrenal suppression in infants.
Key Drug Interactions
- CYP3A inhibitors increase systemic side effects
- Antacids may reduce absorption
- Anticoagulants require monitoring
Contraindications
- Hypersensitivity to prednisolone
- Peptic ulcer
- Osteoporosis
- Active tuberculosis
- Acute infections
Common side effects
- Psychiatric disturbances
- Increased infection risk
- Hypertension
- Gastrointestinal issues
Counselling Points
- Monitor for psychological symptoms
- Avoid live vaccines during treatment
- Gradual dose reduction is crucial
Serious warnings
- Risk of adrenal insufficiency on withdrawal
- Potential for severe psychiatric reactions
- Caution in patients with cardiovascular disease
Important Disclaimer
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