Lerblok 10 & 20 mg FC tablets
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of mild to moderate hypertension.
Dosage (summary)
Starting dose: 10 mg once daily before meals; may increase to 20 mg if needed.
Onset of Action / Duration
Onset: 2 weeks, Duration: 24 hours
Special Populations
- Elderly
- Renal impairment
- Hepatic impairment
Pregnancy & Breastfeeding
Not recommended during pregnancy or breastfeeding.
Key Drug Interactions
- CYP3A4 inhibitors
- Grapefruit juice
- Ciclosporin
Contraindications
- Hypersensitivity
- Severe renal dysfunction
- Severe hepatic dysfunction
- Left ventricular outflow tract obstruction
- Untreated congestive cardiac failure
Common side effects
- Peripheral oedema
- Headache
- Flushing
- Tachycardia
- Palpitations
Counselling Points
- Take at least 15 minutes before meals.
- Avoid grapefruit juice and alcohol.
- Monitor for signs of hypotension.
Serious warnings
- Caution in sick sinus syndrome
- Increased cardiovascular risk in ischaemic heart disease
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