Lexib 100 & 200 100 mg, 200 mg Capsule
Clinical Summary
Quick overview from the medicine insert
Indication
Symptomatic treatment of inflammation and pain in osteoarthritis and rheumatoid arthritis.
Dosage (summary)
Osteoarthritis: 200 mg daily; Rheumatoid arthritis: 100-200 mg twice daily; Pain post dental surgery: 100-200 mg; Mild to moderate dysmenorrhea: 400 mg initially.
Special Populations
- Elderly
- Hepatic impairment
- Renal impairment
Pregnancy & Breastfeeding
Contraindicated in pregnancy and breastfeeding; may cause malformations in animals.
Key Drug Interactions
- Warfarin
- ACE-inhibitors
- Diuretics
- Lithium
Contraindications
- Hypersensitivity to celecoxib
- Active peptic ulceration
- Severe hepatic impairment
- Severe renal impairment
- Asthma related to NSAIDs
Common side effects
- Nausea
- Dizziness
- Hypertension
- Rash
- Myocardial infarction
Counselling Points
- Monitor for GI symptoms
- Avoid alcohol
- Report any skin reactions
- Use contraception during treatment
Serious warnings
- Increased cardiovascular risk
- Gastrointestinal complications
- Serious skin reactions
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