Licax 250 Mg/ 500 Mg 250 mg/ 500 mg POWDER FOR INJECTION
PDF Leaflet Revision Date: 05/02/2021
Clinical Summary
Quick overview from the medicine insert
Indication
Infections caused by penicillinase-producing staphylococci.
Dosage (summary)
250 mg IM every 4-6 hours; 500 mg IV every 4-6 hours.
Onset of Action / Duration
Onset: 1 hour, Duration: 6 hours
Special Populations
- Jaundiced neonates
Pregnancy & Breastfeeding
Safety not established; crosses placenta and into breast milk.
Key Drug Interactions
- Bacteriostatic antibacterials
- Anticoagulants
- Oral contraceptives
- Methotrexate
Contraindications
- Hypersensitivity to cloxacillin
- History of penicillin allergy
- Neonates of penicillin-sensitive mothers
Common side effects
- Skin rashes
- Angioedema
- Bronchospasm
- Anaphylaxis
- Convulsions
Counselling Points
- Monitor for allergic reactions
- Take on an empty stomach for better absorption
- Avoid use in certain populations
Serious warnings
- Risk of neurotoxicity in high doses
- Sensitivity reactions may occur
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