Loperastat Syrup 1 mg per 5 ml Syrup
PDF Leaflet Revision Date: 14 March 2023
Clinical Summary
Quick overview from the medicine insert
Indication
Symptomatic relief of acute and chronic non-specific diarrhoea.
Dosage (summary)
5 ml per 12.5 kg body mass; max 15 ml per 12.5 kg daily.
Special Populations
- Elderly
- Hepatic impairment
Pregnancy & Breastfeeding
Not recommended during pregnancy and breastfeeding.
Key Drug Interactions
- P-glycoprotein inhibitors
- CYP3A4 inhibitors
Contraindications
- Hypersensitivity to loperamide
- Infants < 24 months
- Acute dysentery
- Acute ulcerative colitis
- Bacterial enterocolitis
Common side effects
- Constipation
- Nausea
- Dizziness
- Headache
Counselling Points
- Stop if no improvement in 48 hours
- Hydration is crucial in diarrhoea
- Use caution when driving or operating machinery
Serious warnings
- Risk of toxic megacolon in AIDS patients
- Monitor for CNS toxicity in hepatic impairment
Important Disclaimer
The Loperastat Syrup 1 mg per 5 ml Syrup professional information leaflet below is the property of Ranbaxy Pharmaceuticals and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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