Menograine 25 μg Tablets
PDF Leaflet Revision Date: 24 November 2022
Clinical Summary
Quick overview from the medicine insert
Indication
Prevention of migraine.
Dosage (summary)
Adults: 1 tablet morning and night, may increase to 3 tablets twice daily if necessary.
Special Populations
- Renal impairment
- Cerebrovascular disease
- Heart disease
- Depression history
Pregnancy & Breastfeeding
Use with caution; not recommended in pregnancy, especially first trimester; excreted in breast milk.
Key Drug Interactions
- Methylphenidate
- Tricyclic antidepressants
- Beta-blockers
- CNS depressants
Contraindications
- Hypersensitivity to clonidine
- Porphyria
- Severe bradydysrhythmia
Common side effects
- Drowsiness
- Dry mouth
- Dizziness
- Headache
Counselling Points
- Do not stop therapy without consulting a healthcare provider
- Carry a reserve supply of tablets
- Avoid driving or operating machinery if drowsy
Serious warnings
- Risk of rebound hypertension on withdrawal
- Caution in patients with cardiac conduction abnormalities
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