Merional Hg 75 IU Powder for solution for injection and diluent.
Clinical Summary
Quick overview from the medicine insert
Indication
Indicated for anovulation and stimulation of multifollicular development in assisted reproductive technologies.
Dosage (summary)
Start with 75-150 IU daily, max 225 IU; adjust based on response.
Special Populations
- Renal impairment
- Hepatic impairment
Pregnancy & Breastfeeding
Contraindicated in pregnancy and breastfeeding.
Key Drug Interactions
- Concomitant use with hCG or clomifene may potentiate response
- GnRH agonists may increase dosage needed
Contraindications
- Hypersensitivity to menotrophin
- Tumours of hypothalamus or pituitary
- Ovarian enlargement not due to PCOD
- Gynaecological haemorrhages of unknown cause
- Ovarian, uterine or mammary carcinoma
Common side effects
- Headache
- Abdominal pain
- Nausea
- Weight gain
- Ovarian cysts
Counselling Points
- Monitor for signs of OHSS
- Adhere to dosing regimen
- Discuss risks of multiple pregnancies
Serious warnings
- Risk of ovarian hyperstimulation syndrome (OHSS)
- Potential for multiple pregnancies
- Monitor for thromboembolic events
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