Mylan Methylprednisolone 40mg/120mg/500mg/1000mg Powder for solution for injection
Clinical Summary
Quick overview from the medicine insert
Indication
Corticosteroid for various inflammatory and autoimmune conditions.
Dosage (summary)
IV: 30 mg/kg for life-threatening conditions; 1 g/day for 3 days for SLE or MS.
Special Populations
- Renal impairment
- Hepatic impairment
Pregnancy & Breastfeeding
Safety in pregnancy not established; excreted in breast milk, may cause adrenal suppression in infants.
Key Drug Interactions
- Ciclosporin
- Rifampicin
- Erythromycin
- Diuretics
- Antidiabetic agents
Contraindications
- Active viral infections
- Psychotic states
- Live vaccines
- Hypersensitivity
- Systemic fungal infections
Common side effects
- Gastrointestinal irritation
- Increased appetite
- Weight gain
- Nervousness
- Sleep disturbances
Counselling Points
- Monitor for signs of infection
- Do not stop abruptly after long-term use
- Avoid live vaccines
Serious warnings
- Risk of anaphylaxis
- May mask infections
- Adrenal insufficiency on withdrawal
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