Nepizel 5 & 10 5,0 mg or 10,0 mg FC tablets.
PDF Leaflet Revision Date: 05 June 2023
Clinical Summary
Quick overview from the medicine insert
Indication
Symptomatic treatment of mild to moderate dementia in Alzheimeru2019s disease.
Dosage (summary)
Adults/elderly: Start at 5 mg once daily, may increase to 10 mg after 4-6 weeks.
Special Populations
- Renal impairment
- Hepatic impairment
Pregnancy & Breastfeeding
Not recommended during pregnancy or breastfeeding.
Key Drug Interactions
- CYP3A4 inhibitors
- CYP2D6 inhibitors
- NSAIDs
Contraindications
- Hypersensitivity to donepezil
- Pregnancy
- Lactation
- Children
- Post-surgery recovery
Common side effects
- Diarrhoea
- Muscle cramps
- Fatigue
- Nausea
- Vomiting
Counselling Points
- Take in the evening before bed
- Monitor for gastrointestinal symptoms
- Avoid abrupt discontinuation
Serious warnings
- Monitor for bradycardia
- Risk of QTc prolongation
- Potential for seizures
Important Disclaimer
The Nepizel 5 & 10 5,0 mg or 10,0 mg FC tablets. professional information leaflet below is the property of Unichem Sa and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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