Nexium Sachet & Tablet
PDF Leaflet Revision Date: 02 October 2015
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of Gastro-oesophageal Reflux Disease (GORD) and prevention of NSAID-related ulcers.
Dosage (summary)
20 mg once daily for maintenance; 40 mg once daily for erosive reflux treatment.
Onset of Action / Duration
Onset: 1 hour, Duration: 24 hours
Special Populations
- Elderly
- Renal impairment
- Hepatic impairment
Pregnancy & Breastfeeding
Safety not established during pregnancy and lactation.
Key Drug Interactions
- Clopidogrel
- Warfarin
- Atazanavir
- Nelfinavir
Contraindications
- Hypersensitivity to esomeprazole
- Concomitant use with atazanavir or nelfinavir
Common side effects
- Headache
- Abdominal pain
- Diarrhoea
- Nausea
Counselling Points
- Take tablets whole; do not chew or crush.
- Monitor for gastrointestinal symptoms.
- Avoid alcohol and NSAIDs.
Serious warnings
- May mask gastric malignancy symptoms
- Increased risk of gastrointestinal infections
Important Disclaimer
The Nexium Sachet & Tablet professional information leaflet below is the property of Astrazeneca and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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