Pariet 10 Mg And 20 Mg 10 mg/20 mg Oral tablets
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of active duodenal and gastric ulcers, GORD, and Zollinger-Ellison Syndrome.
Dosage (summary)
20 mg once daily for duodenal/gastric ulcers; 10 mg for maintenance GORD.
Onset of Action / Duration
Onset: 1 hour, Duration: up to 48 hours
Special Populations
- Renal impairment
- Hepatic impairment
Pregnancy & Breastfeeding
Contraindicated in pregnancy and breastfeeding.
Key Drug Interactions
- Atazanavir
- Methotrexate
- Digoxin
Contraindications
- Hypersensitivity to rabeprazole
- Pregnancy
- Lactation
- Acute tubulointerstitial nephritis
Common side effects
- Headache
- Diarrhoea
- Abdominal pain
- Rash
- Dry mouth
Counselling Points
- Take in the morning before food
- Do not chew or crush tablets
- Monitor for magnesium levels if on long-term therapy
Serious warnings
- Hypomagnesaemia
- Increased risk of fractures
- Gastrointestinal infections
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