Pethidine 50 Mg And 100 Mg Unimed 50 mg and 100 mg Injection
PDF Leaflet Revision Date: 22 August 2025
Clinical Summary
Quick overview from the medicine insert
Indication
Relief of pain, including obstetric and post-operative pain.
Dosage (summary)
Adults: 50-100 mg IM/SC/IV every 4 hours as needed; during labor: 50-100 mg IM every 1-3 hours.
Onset of Action / Duration
Onset: 10 mins, Duration: 3-5 hours
Special Populations
- Elderly
- Debilitated patients
- Renal impairment
- Hepatic impairment
- Neonates
Pregnancy & Breastfeeding
Crosses placenta; may cause respiratory depression in newborns. Discontinue breastfeeding during treatment.
Key Drug Interactions
- MAOIs
- CNS depressants
- SSRIs
- Ritonavir
- Phenothiazines
Contraindications
- Hypersensitivity to pethidine
- Respiratory depression
- Acute alcoholism
- Convulsive disorders
- Head injuries
- Bronchial asthma
- Heart failure
- Severe renal impairment
- Severe hepatic impairment
Common side effects
- Drowsiness
- Nausea
- Respiratory depression
- Hypotension
- Dependence
Counselling Points
- Avoid driving or operating machinery
- Monitor for signs of respiratory depression
- Inform about potential for dependence
Serious warnings
- Risk of dependence
- Respiratory depression in newborns
- Caution in patients with airflow obstruction
Important Disclaimer
The Pethidine 50 Mg And 100 Mg Unimed 50 mg and 100 mg Injection professional information leaflet below is the property of Unimed Healthcare and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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