Rapifen 0.5mg / 2ml Injection
PDF Leaflet Revision Date: 12 May 2023
Clinical Summary
Quick overview from the medicine insert
Indication
Narcotic analgesic for general anaesthesia.
Dosage (summary)
Initial IV bolus of 7-15 u03bcg/kg for short procedures; adjust for age and condition.
Onset of Action / Duration
Onset: 1 min, Duration: 11-17 mins
Special Populations
- Elderly
- Hepatic impairment
- Renal impairment
Pregnancy & Breastfeeding
Not established safe in pregnancy; avoid during childbirth; may enter breast milk.
Key Drug Interactions
- MAO inhibitors
- CYP3A4 inhibitors
- Other CNS depressants
Contraindications
- Intolerance to opioids
- Respiratory depression risk
- Myasthenia gravis
Common side effects
- Respiratory depression
- Bradycardia
- Nausea
- Muscle rigidity
Counselling Points
- Ensure monitoring equipment available
- Have naloxone ready
- Avoid driving for 6-24 hours post-dose
Serious warnings
- Risk of bradycardia and cardiac arrest
- Monitor heart rate
- Avoid rapid bolus injections
Important Disclaimer
The Rapifen 0.5mg / 2ml Injection professional information leaflet below is the property of Piramal Critical Care and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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