Sevcad 100 Mg. Sevcad 150 Mg 100 mg. 150 mg Soft gelatin capsules
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of Idiopathic Pulmonary Fibrosis and other chronic fibrosing ILDs.
Dosage (summary)
150 mg every 12 hours; 100 mg if 150 mg is not tolerated.
Special Populations
- Elderly patients
- Renal impairment
- Hepatic impairment
Pregnancy & Breastfeeding
Not recommended during pregnancy; use effective contraception. Breastfeeding should be discontinued.
Key Drug Interactions
- P-glycoprotein inhibitors
- P-glycoprotein inducers
Contraindications
- Hypersensitivity to nintedanib or soya
- Pregnancy
Common side effects
- Diarrhoea
- Nausea
- Vomiting
- Increased hepatic enzymes
Counselling Points
- Take with food
- Monitor for gastrointestinal symptoms
- Avoid pregnancy during treatment
Serious warnings
- Risk of gastrointestinal perforation
- Increased risk of bleeding
- Liver injury
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