Simvotin 10/20/40 10/20/40 mg Tablets
Clinical Summary
Quick overview from the medicine insert
Indication
Management of hypercholesterolaemia and coronary heart disease.
Dosage (summary)
Starting dose 10 mg/day in the evening; max 80 mg/day.
Special Populations
- Renal impairment
- Elderly
Pregnancy & Breastfeeding
Contraindicated in pregnancy and breastfeeding.
Key Drug Interactions
- CYP3A4 inhibitors
- Gemfibrozil
- Ciclosporin
Contraindications
- Hypersensitivity
- Liver disease
- Pregnancy
- Breastfeeding
Common side effects
- Myopathy
- Muscle cramps
- Headache
- Dizziness
Counselling Points
- Report unexplained muscle pain
- Avoid grapefruit juice
- Monitor blood glucose levels
Serious warnings
- Risk of myopathy/rhabdomyolysis
- Liver function monitoring required
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