Sumabid 100 Iv 100 mg Solution for Injection.
Clinical Summary
Quick overview from the medicine insert
Indication
Routine and immediate reversal of neuromuscular blockade induced by rocuronium or vecuronium.
Dosage (summary)
4 mg/kg for profound blockade, 2 mg/kg for shallow blockade, 16 mg/kg for immediate reversal.
Onset of Action / Duration
Onset: 3 mins, Duration: varies.
Special Populations
- Renal impairment
- Hepatic impairment
- Elderly patients
- Obese patients
- Paediatric patients
Pregnancy & Breastfeeding
Caution in pregnancy; unknown if excreted in breast milk.
Key Drug Interactions
- Toremifene
- Fusidic acid
- Hormonal contraceptives
Contraindications
- Hypersensitivity to sugammadex
Common side effects
- Cough
- Dysgeusia
- Airway complications
- Procedural hypotension
Counselling Points
- Monitor for signs of recurrence of neuromuscular blockade.
- Inform about potential hypersensitivity reactions.
- Advise on the need for ventilatory support post-reversal.
Serious warnings
- Risk of recurrence of neuromuscular blockade
- Marked bradycardia
- Monitor respiratory function post-reversal
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