Synapause Vaginal Cream 1mg CREAM
PDF Leaflet Revision Date: 06 June 2014
Clinical Summary
Quick overview from the medicine insert
Indication
Hormone replacement therapy for urogenital atrophy.
Dosage (summary)
1 application daily for 2-3 weeks, then reduce to 1 application twice a week.
Special Populations
- Elderly
- Postmenopausal women
Pregnancy & Breastfeeding
Contraindicated in pregnancy and lactation; may decrease milk production.
Key Drug Interactions
- Anticonvulsants
- Antibiotics
- St. John's wort
Contraindications
- Hypersensitivity
- Breast cancer
- Oestrogen-dependent tumors
- Undiagnosed vaginal bleeding
- Venous thromboembolism
- Pregnancy
- Liver disease
Common side effects
- Breast tenderness
- Breakthrough bleeding
- Local irritation
- Gall bladder disease
Counselling Points
- Report any unusual breast changes
- Avoid use if pregnant
- Use the lowest effective dose for the shortest duration
Serious warnings
- Increased risk of breast cancer
- Risk of venous thromboembolism
- Increased risk of stroke
- Monitor for liver function
Important Disclaimer
The Synapause Vaginal Cream 1mg CREAM professional information leaflet below is the property of Pharmacare and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
Healthcare Professionals Only
This content is for registered healthcare professionals
Sign in or create a free account to read the full package insert.
Free for HPCSA-registered professionals. Powered by Medinsert.
