Tazatred 20/50/70/100 20 mg, 50 mg, 70 mg, 100 mg Tablet

    Tazatred 20/50/70/100 20 mg, 50 mg, 70 mg, 100 mg Tablet

    S4
    PDF Leaflet Revision Date: 24 March 2023


    Clinical Summary

    Quick overview from the medicine insert

    Indication

    Treatment of adults with Ph+ CML and Ph+ ALL.

    Dosage (summary)

    100 mg once daily for chronic phase CML; 70 mg twice daily for advanced phase CML or Ph+ ALL.

    Special Populations

    • Renal impairment
    • Hepatic impairment
    • Elderly population

    Pregnancy & Breastfeeding

    Not recommended in pregnancy; contraindicated in breastfeeding.

    Key Drug Interactions

    • CYP3A4 inhibitors
    • CYP3A4 inducers
    • H2 antagonists
    • Proton pump inhibitors

    Contraindications

    • Hypersensitivity to dasatinib
    • Concomitant use of H2 antagonists or PPIs

    Common side effects

    • Myelosuppression
    • Fluid retention
    • Cardiac adverse reactions

    Counselling Points

    • Take consistently with or without food
    • Monitor for signs of bleeding
    • Use contraception during treatment

    Serious warnings

    • Myelosuppression
    • Severe bleeding events
    • Pulmonary arterial hypertension
    Important Disclaimer

    The Tazatred 20/50/70/100 20 mg, 50 mg, 70 mg, 100 mg Tablet professional information leaflet below is the property of Dr Reddy’S Laboratories and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>

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