Tonatadin 400/50 Mg 400 mg, 40 mg Tablet
PDF Leaflet Revision Date: 25 July 2023
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of HIV in antiretroviral treatment experienced adults.
Dosage (summary)
800/100 mg once daily with food.
Special Populations
- Elderly
- Renal impairment
- Hepatic impairment
Pregnancy & Breastfeeding
Contraindicated in pregnancy and breastfeeding.
Key Drug Interactions
- CYP3A inhibitors
- Anticonvulsants
- Antihistamines
- Ergot derivatives
Contraindications
- Hypersensitivity to darunavir or ritonavir
- Severe hepatic impairment
Common side effects
- Rash
- Nausea
- Diarrhea
- Headache
Counselling Points
- Take with food
- Monitor for skin reactions
- Avoid certain drug interactions
Serious warnings
- Severe skin reactions
- Hepatotoxicity
- Immune reconstitution inflammatory syndrome
Important Disclaimer
The Tonatadin 400/50 Mg 400 mg, 40 mg Tablet professional information leaflet below is the property of Hetero Drugs South Africa and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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