Trelavue 50mg. 600mg. 300mg Tablet
PDF Leaflet Revision Date: 21 April 2016
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of HIV infection in adults and adolescents.
Dosage (summary)
One tablet once daily for adults and adolescents over 40 kg.
Special Populations
- Renal impairment
- Hepatic impairment
- Elderly
Pregnancy & Breastfeeding
Contraindicated in pregnancy and breastfeeding due to potential teratogenicity.
Key Drug Interactions
- Dofetilide
- Pilsicainide
- Metformin
- Antacids containing polyvalent cations
Contraindications
- Hypersensitivity to components
- Moderate and severe hepatic impairment
- Creatinine clearance < 50 ml/min
Common side effects
- Hypersensitivity reactions
- Nausea
- Diarrhoea
- Fatigue
- Rash
Counselling Points
- Inform about hypersensitivity risks and symptoms.
- Never restart TRELAVUE after hypersensitivity.
- Monitor for signs of lactic acidosis.
- Avoid breastfeeding while on TRELAVUE.
Serious warnings
- Severe hypersensitivity reactions
- Lactic acidosis
- Osteonecrosis
- Pancreatitis
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