Tygacil 50mg / 5ml Infusion
PDF Leaflet Revision Date: 20 October 2006
Clinical Summary
Quick overview from the medicine insert
Indication
Severe life-threatening infections in adults.
Dosage (summary)
100 mg IV initially, then 50 mg every 12 hours.
Onset of Action / Duration
Onset: 30 mins, Duration: 5-14 days
Special Populations
- Hepatic impairment
- Renal impairment
- Elderly
Pregnancy & Breastfeeding
Contraindicated in pregnancy; unknown if excreted in human milk.
Key Drug Interactions
- Warfarin (increased AUC)
- Digoxin (slight decrease in C max)
Contraindications
- Hypersensitivity to TYGACIL
Common side effects
- Nausea
- Vomiting
- Diarrhoea
- Dizziness
Counselling Points
- Monitor for signs of allergic reactions.
- Report any gastrointestinal symptoms.
- Avoid use in pregnancy.
Serious warnings
- Anaphylaxis risk
- Pseudomembranous colitis
- Tooth discoloration
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