Vasloc 5mg; 10 mg Tablets.
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of angina pectoris and mild to moderate hypertension.
Dosage (summary)
Initial dose 5 mg once daily, may increase to 10 mg after 10-14 days.
Onset of Action / Duration
Onset: 6-12 hours, Duration: 24 hours
Special Populations
- Elderly
- Renal impairment
- Hepatic impairment
Pregnancy & Breastfeeding
Contraindicated in pregnancy and breastfeeding.
Key Drug Interactions
- CYP3A4 inhibitors
- CYP3A4 inducers
- Grapefruit juice
- Lithium
Contraindications
- Hypersensitivity to amlodipine
- Severe hypotension
- Shock
- Obstruction of left ventricle outflow
- Unstable angina
- Pregnancy and lactation
Common side effects
- Dizziness
- Headache
- Fatigue
- Nausea
- Ankle swelling
Counselling Points
- Monitor blood pressure regularly
- Avoid sudden discontinuation
- Caution when driving or operating machinery
Serious warnings
- Caution in heart failure
- Risk of hypotension
- Gradual withdrawal recommended
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