Venclexta 10 Mg FC Tablets. Venclexta 50 Mg FC Tablets. Venclexta 100 Mg FC Tablets 10 mg. 50 mg. 100 mg FC tablet
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of CLL and AML in adults.
Dosage (summary)
Starting dose 20 mg daily, titrated to 400 mg over 5 weeks.
Onset of Action / Duration
Onset: 6-8 hours, Duration: Not specified.
Special Populations
- Elderly
- Renal impairment
- Hepatic impairment
Pregnancy & Breastfeeding
Contraindicated in pregnancy; avoid breastfeeding.
Key Drug Interactions
- Strong CYP3A inhibitors
- Moderate CYP3A inducers
Contraindications
- Hypersensitivity
- Concomitant use of strong CYP3A inhibitors
Common side effects
- Neutropenia
- Diarrhoea
- Fatigue
- Nausea
Counselling Points
- Take with food
- Hydration to prevent TLS
- Monitor for infections
Serious warnings
- Tumour lysis syndrome
- Serious infections
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