Videx Ec 250mg & 400mg Capsule
Clinical Summary
Quick overview from the medicine insert
Indication
Palliative treatment of adults with advanced HIV infection.
Dosage (summary)
400 mg once daily for u2265 60 kg; 250 mg once daily for < 60 kg.
Special Populations
- Renal impairment
- Hepatic impairment
- Elderly patients
Pregnancy & Breastfeeding
Not established as safe in pregnancy; avoid breastfeeding.
Key Drug Interactions
- Allopurinol
- Tenofovir disoproxil fumarate
- Ribavirin
Contraindications
- Hypersensitivity to didanosine
- Severe hepatic impairment
Common side effects
- Pancreatitis
- Peripheral neuropathy
- Diarrhoea
- Nausea
- Fatigue
Counselling Points
- Take on an empty stomach
- Monitor for pancreatitis symptoms
- Avoid alcohol
Serious warnings
- Pancreatitis risk
- Lactic acidosis
- Hepatic failure
- Non-cirrhotic portal hypertension
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