Volmaro 5 mg &10 mg FC Tablets

Volmaro 5 mg &10 mg FC Tablets

S4
PDF Leaflet Revision Date: 30 March 2022

API: Ambrisentan | Company: Cipla Medpro

Clinical Summary

Quick overview from the medicine insert

Indication

Treatment of pulmonary arterial hypertension (PAH).

Dosage (summary)

5 mg once daily, may increase to 10 mg if tolerated.

Special Populations

  • Elderly
  • Renal impairment
  • Hepatic impairment

Pregnancy & Breastfeeding

Contraindicated in pregnancy; breastfeeding not recommended.

Key Drug Interactions

  • Ciclosporin A
  • Ketoconazole
  • Rifampicin
  • Warfarin

Contraindications

  • Pregnancy
  • Breastfeeding
  • Severe hepatic impairment

Common side effects

  • Peripheral oedema
  • Headache
  • Anaemia
  • Dizziness

Counselling Points

  • Avoid in pregnancy; reliable contraception required.
  • Monitor for signs of hepatic injury.
  • Report any signs of anaemia.

Serious warnings

  • Hepatic injury
  • Autoimmune hepatitis
  • Fluid retention

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Volmaro 5 mg &10 mg FC Tablets
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