Volutrip Tablets
PDF Leaflet Revision Date: 22 January 2025
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of HIV infection in adults aged 18 years and older.
Dosage (summary)
One tablet orally once daily, without regard to food.
Special Populations
- Renal impairment
- Hepatic impairment
Pregnancy & Breastfeeding
Contraindicated in pregnancy; potential risk of neural tube defects. Not recommended during breastfeeding.
Key Drug Interactions
- Rifampicin decreases dolutegravir levels
- Metformin contraindicated
- Avoid antacids containing polyvalent cations
Contraindications
- Moderate or severe hepatic impairment
- Renal impairment with creatinine clearance < 80 ml/min
- Hypersensitivity to components
Common side effects
- Nausea
- Diarrhoea
- Headache
Counselling Points
- Use effective contraception in women of childbearing age
- Monitor renal function regularly
- Inform about potential side effects and when to seek medical help
Serious warnings
- Lactic acidosis and severe hepatomegaly reported
- Risk of opportunistic infections
- Monitor for hypersensitivity reactions
Important Disclaimer
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