VoXRa Xl 150mg. 300mg Tablet

Indication

Treatment of depression as per DSM IV criteria.

Dosage (summary)

Initial: 150 mg once daily; may increase to 300 mg once daily if needed.

Special Populations

• Elderly
• Renal impairment
• Hepatic impairment

Pregnancy & Breastfeeding

Not established; avoid unless necessary. Contraindicated in breastfeeding.

Key Drug Interactions

• CYP2B6 inhibitors
• MAOIs
• Alcohol

Contraindications

• Hypersensitivity to bupropion
• Seizure disorder
• Patients under 18 years
• Bulimia or anorexia nervosa
• Moderate to severe hepatic cirrhosis

Common side effects

• Insomnia
• Headache
• Dry mouth
• Increased blood pressure

Counselling Points

• Monitor for worsening depression or suicidal thoughts.
• Avoid alcohol during treatment.
• Do not crush or chew tablets.