Wellbutrin Xl 150mg & 300mg ER Tablets
PDF Leaflet Revision Date: 23 April 2024
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of depression as per DSM IV criteria.
Dosage (summary)
Initial: 150 mg once daily; may increase to 300 mg once daily after 24 hours if needed.
Special Populations
- Elderly
- Renal impairment
- Hepatic impairment
Pregnancy & Breastfeeding
Not established; avoid unless necessary. Contraindicated in breastfeeding.
Key Drug Interactions
- CYP2B6 inhibitors
- MAOIs
- Serotonergic agents
Contraindications
- Hypersensitivity to bupropion
- Seizure disorder
- Patients under 18 years
- Bulimia or anorexia nervosa
- Moderate to severe hepatic cirrhosis
Common side effects
- Insomnia
- Headache
- Dry mouth
- Increased blood pressure
Counselling Points
- Avoid alcohol during treatment.
- Monitor for worsening depression or suicidal thoughts.
- Do not crush or chew tablets.
Serious warnings
- Risk of seizures
- Suicidal ideation in young adults
- Neuropsychiatric symptoms
Important Disclaimer
The Wellbutrin Xl 150mg & 300mg ER Tablets professional information leaflet below is the property of Glaxosmithkline South Africa (Edms) Bpk and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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