Xefo 8 Iv/Im 8 mg Water for Injection

Xefo 8 Iv/Im 8 mg Water for Injection

S3
PDF Leaflet Revision Date: 31 October 2024

API: Lornoxicam | Company: Acino Pharma

Clinical Summary

Quick overview from the medicine insert

Indication

Short term treatment of mild to moderate pain when oral administration is inappropriate.

Dosage (summary)

8 mg IV/IM, max 16 mg/day; may require additional 8 mg within 24 hours.

Onset of Action / Duration

Onset: 20-25 mins, Duration: 6-8 hours

Special Populations

  • Elderly
  • Renal impairment
  • Hepatic impairment
  • Children and adolescents

Pregnancy & Breastfeeding

Contraindicated in third trimester; caution in first and second trimesters; not recommended in breastfeeding.

Key Drug Interactions

  • Anticoagulants (e.g., Warfarin)
  • Diuretics
  • Lithium
  • Methotrexate
  • Corticosteroids

Contraindications

  • Allergy to lornoxicam
  • Severe renal impairment
  • Severe hepatic impairment
  • Active peptic ulcer
  • Pregnancy
  • Lactation
  • Children under 18

Common side effects

  • Nausea
  • Dyspepsia
  • Abdominal pain
  • Vomiting
  • Diarrhoea

Counselling Points

  • Use lowest effective dose for shortest duration.
  • Monitor for gastrointestinal symptoms.
  • Avoid in pregnancy and breastfeeding.
  • Caution in elderly and those with renal/hepatic impairment.

Serious warnings

  • Gastrointestinal bleeding
  • Cardiovascular events
  • Serious skin reactions
  • Renal impairment monitoring
Important Disclaimer

The Xefo 8 Iv/Im 8 mg Water for Injection professional information leaflet below is the property of Acino Pharma and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>

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