Xefo 8 Iv/Im 8 mg Water for Injection
Clinical Summary
Quick overview from the medicine insert
Indication
Short term treatment of mild to moderate pain when oral administration is inappropriate.
Dosage (summary)
8 mg IV/IM, max 16 mg/day; may require additional 8 mg within 24 hours.
Onset of Action / Duration
Onset: 20-25 mins, Duration: 6-8 hours
Special Populations
- Elderly
- Renal impairment
- Hepatic impairment
- Children and adolescents
Pregnancy & Breastfeeding
Contraindicated in third trimester; caution in first and second trimesters; not recommended in breastfeeding.
Key Drug Interactions
- Anticoagulants (e.g., Warfarin)
- Diuretics
- Lithium
- Methotrexate
- Corticosteroids
Contraindications
- Allergy to lornoxicam
- Severe renal impairment
- Severe hepatic impairment
- Active peptic ulcer
- Pregnancy
- Lactation
- Children under 18
Common side effects
- Nausea
- Dyspepsia
- Abdominal pain
- Vomiting
- Diarrhoea
Counselling Points
- Use lowest effective dose for shortest duration.
- Monitor for gastrointestinal symptoms.
- Avoid in pregnancy and breastfeeding.
- Caution in elderly and those with renal/hepatic impairment.
Serious warnings
- Gastrointestinal bleeding
- Cardiovascular events
- Serious skin reactions
- Renal impairment monitoring
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