Xonocod XR Tablet
PDF Leaflet Revision Date: 15 August 2023
Clinical Summary
Quick overview from the medicine insert
Indication
Severe pain requiring strong opioid analgesic.
Dosage (summary)
Starting dose: 10 mg/5 mg every 12 hours; max: 80 mg oxycodone/40 mg naloxone daily.
Special Populations
- Elderly patients
- Hepatic impairment
- Renal impairment
Pregnancy & Breastfeeding
Not recommended during pregnancy or breastfeeding.
Key Drug Interactions
- CNS depressants
- Benzodiazepines
- Alcohol
- MAO inhibitors
Contraindications
- Hypersensitivity to components
- Severe respiratory depression
- Severe COPD
- Severe asthma
- Moderate to severe hepatic impairment
- Moderate to severe renal impairment
Common side effects
- Constipation
- Nausea
- Somnolence
- Dizziness
- Headache
Counselling Points
- Take whole, do not chew or crush.
- Monitor for signs of respiratory depression.
- Avoid alcohol and CNS depressants.
Serious warnings
- Risk of respiratory depression
- Potential for addiction
- Caution in hepatic/renal impairment
Important Disclaimer
The Xonocod XR Tablet professional information leaflet below is the property of Austell Pharmaceuticals and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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