Yervoy 5mg/ml Solution for Infusion
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of previously treated unresectable or metastatic melanoma in adults.
Dosage (summary)
3 mg/kg IV over 90 mins every 3 weeks for 4 doses.
Special Populations
- Elderly
- Renal impairment
- Hepatic impairment
Pregnancy & Breastfeeding
Not recommended during pregnancy; unknown if excreted in breast milk.
Key Drug Interactions
- Corticosteroids
- Anticoagulants
Contraindications
- Hypersensitivity to ipilimumab or excipients
Common side effects
- Diarrhoea
- Rash
- Pruritus
- Fatigue
- Nausea
Counselling Points
- Monitor for immune-related adverse reactions
- Avoid during pregnancy
- Use contraception during treatment
Serious warnings
- Severe immune-mediated reactions
- Gastrointestinal perforation
- Hepatotoxicity
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