Pixeclot 2,5 Mg & 5 Mg 2,5 mg, 5 mg Tablet
PDF Leaflet Revision Date: 10 October 2023
Clinical Summary
Quick overview from the medicine insert
Indication
Prevention of VTE and stroke in NVAF patients.
Dosage (summary)
2.5 mg twice daily for VTE; 5 mg twice daily for NVAF.
Special Populations
- Renal impairment
- Hepatic impairment
- Elderly
Pregnancy & Breastfeeding
Avoid in pregnancy; unknown if excreted in breast milk.
Key Drug Interactions
- Strong CYP3A4 and P-gp inhibitors
- Anticoagulants
- Antiplatelet agents
Contraindications
- Hypersensitivity to apixaban
- Active bleeding
- Severe renal disease
- Severe hepatic impairment
Common side effects
- Haemorrhage
- Contusion
- Epistaxis
- Haematoma
Counselling Points
- Take with or without food
- Monitor for signs of bleeding
- Do not crush tablets unless necessary
Serious warnings
- Increased bleeding risk
- No reversal agent available
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