Cosyrel 5 mg/5 mg, 5 mg/10 mg, 10 mg/5 mg, 10 mg/10 mg film-coated tablets
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of hypertension and/or stable coronary artery disease and/or stable chronic heart failure.
Dosage (summary)
One tablet once daily; adjust for renal impairment.
Special Populations
- Renal impairment
- Hepatic impairment
- Elderly
Pregnancy & Breastfeeding
Contraindicated in pregnancy and breastfeeding.
Key Drug Interactions
- Potassium-sparing diuretics
- Lithium
- Aliskiren
- Sacubitril/valsartan
Contraindications
- Hypersensitivity
- Acute heart failure
- Cardiogenic shock
- Second or third degree AV block
- Sick sinus syndrome
- Symptomatic bradycardia
- Severe bronchial asthma
Common side effects
- Headache
- Dizziness
- Hypotension
- Nausea
- Vomiting
Counselling Points
- Take in the morning before meals
- Monitor blood pressure regularly
- Report any signs of angioedema immediately
Serious warnings
- Hypotension
- Angioedema
- Neutropenia
- Hepatic failure
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