Bupropion 150 Mg & 300 Mg XR Dyna 150 mg, 300 mg Tablet
PDF Leaflet Revision Date: 27 June 2023
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of depression.
Dosage (summary)
Initial: 150 mg once daily; may increase to 300 mg once daily.
Special Populations
- Elderly
- Renal impairment
- Hepatic impairment
Pregnancy & Breastfeeding
Not established; avoid breastfeeding.
Key Drug Interactions
- CYP2B6 inhibitors
- MAOIs
- Alcohol
Contraindications
- Hypersensitivity
- Seizure disorder
- Patients under 18 years
- Bulimia or anorexia nervosa
- Abrupt discontinuation of alcohol or sedatives
Common side effects
- Insomnia
- Agitation
- Dry mouth
- Headache
Counselling Points
- Monitor for worsening depression
- Avoid alcohol
- Do not crush or chew tablets
Serious warnings
- Risk of seizures
- Suicidal ideation
- Neuropsychiatric symptoms
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