Degranol 700mg Tablet
PDF Leaflet Revision Date: 19 March 1985
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of epilepsy and trigeminal neuralgia.
Dosage (summary)
Epilepsy: 100-200 mg once/twice daily, increase to 400 mg 2-3 times daily. Trigeminal Neuralgia: 200 mg twice daily, increase as needed.
Special Populations
- Elderly
- Hepatic impairment
- Renal impairment
Pregnancy & Breastfeeding
Safety in pregnancy not established; passes into breast milk.
Key Drug Interactions
- Alcohol
- Phenytoin
- Doxycycline
- Oral anticoagulants
- Oral contraceptives
Contraindications
- Hypersensitivity to carbamazepine
- Liver disease
- Heart block
- Monoamine oxidase inhibitors
- Porphyria
Common side effects
- Drowsiness
- Dizziness
- Nausea
- Headache
- Dry mouth
Counselling Points
- Avoid alcohol
- Monitor liver function
- Gradual dosage increase recommended
Serious warnings
- Increased liver tumor incidence in rats
- Medicinal supervision required
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