Kocef 250 mg, 500 mg, 1000 mg, INJECTION
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of infections caused by susceptible organisms.
Dosage (summary)
Adults: 1-2 g once daily; severe cases may require up to 4 g.
Special Populations
- Elderly
- Renal impairment
- Hepatic impairment
Pregnancy & Breastfeeding
Crosses placenta; safety not established. Caution in breastfeeding.
Key Drug Interactions
- Calcium-containing products
- Anticoagulants
- Aminoglycosides
Contraindications
- Hypersensitivity to ceftriaxone
- Premature neonates
- Hyperbilirubinemic newborns
Common side effects
- Eosinophilia
- Leucopenia
- Diarrhoea
- Rash
Counselling Points
- Monitor for allergic reactions
- Avoid calcium-containing solutions
- Report any severe gastrointestinal symptoms
Serious warnings
- Serious hypersensitivity reactions
- Clostridium difficile associated diarrhoea
- Risk of precipitation with calcium
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