Celecoxib Pfizer 100 mg. 200 mg Hard capsules
PDF Leaflet Revision Date: 13 February 2022
Clinical Summary
Quick overview from the medicine insert
Indication
Symptomatic treatment of inflammation and pain.
Dosage (summary)
Osteoarthritis: 200 mg daily; Rheumatoid arthritis: 100-200 mg twice daily; Post-operative pain: 100-200 mg; Dysmenorrhoea: 400 mg initially, then 200 mg; Ankylosing spondylitis: 200 mg daily.
Special Populations
- Elderly
- Hepatic impairment
- Renal impairment
- CYP2C9 poor metabolisers
Pregnancy & Breastfeeding
Avoid in pregnancy; excreted in breast milk.
Key Drug Interactions
- Warfarin
- Fluconazole
- Diuretics
- ACE inhibitors
Contraindications
- Hypersensitivity to celecoxib
- Severe hepatic impairment
- Severe renal impairment
- Asthma related to NSAIDs
- Pregnancy
Common side effects
- Hypertension
- Dizziness
- Gastrointestinal upset
- Rash
Counselling Points
- Take with or without food
- Monitor for cardiovascular symptoms
- Report any skin reactions immediately
Serious warnings
- Cardiovascular events risk
- Gastrointestinal complications
- Serious skin reactions
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