Norvasc Tablets 5 mg.10 mg Tablet.

    Norvasc Tablets 5 mg.10 mg Tablet.

    S3
    PDF Leaflet Revision Date: 22 January 2022


    Clinical Summary

    Quick overview from the medicine insert

    Indication

    Treatment of hypertension and angina pectoris.

    Dosage (summary)

    Initial dose 5 mg once daily, may increase to 10 mg based on response.

    Onset of Action / Duration

    Onset: 6-12 hours, Duration: 35-50 hours

    Special Populations

    • Elderly
    • Hepatic impairment
    • Renal failure

    Pregnancy & Breastfeeding

    Safety in pregnancy and lactation not established.

    Key Drug Interactions

    • CYP3A4 inhibitors
    • Simvastatin
    • Clarithromycin

    Contraindications

    • Hypersensitivity to dihydropyridines
    • Grapefruit juice

    Common side effects

    • Dizziness
    • Headache
    • Palpitations
    • Abdominal pain

    Counselling Points

    • Monitor for dizziness
    • Avoid grapefruit juice
    • Report any allergic reactions

    Serious warnings

    • Increased risk of hypotension with CYP3A4 inhibitors
    Important Disclaimer

    The Norvasc Tablets 5 mg.10 mg Tablet. professional information leaflet below is the property of Upjohn South Africa and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>

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