Exsira 50mg. 100mg Tablet
PDF Leaflet Revision Date: 06 March 2014
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of major depressive disorder.
Dosage (summary)
50 mg once daily, max 100 mg; adjust for renal impairment.
Special Populations
- Elderly
- Renal impairment
- Hepatic impairment
Pregnancy & Breastfeeding
Not recommended during pregnancy or lactation.
Key Drug Interactions
- MAOIs
- CNS-active agents
- Serotonin syndrome risk
Contraindications
- Hypersensitivity
- MAOI use
- Children under 18
Common side effects
- Nausea
- Dizziness
- Insomnia
- Fatigue
- Palpitations
Counselling Points
- Monitor for worsening depression
- Avoid alcohol
- Gradual dose tapering recommended
Serious warnings
- Suicidality risk
- Serotonin syndrome
- Increased blood pressure
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