Farmorubicin 10mg / 5ml. 20mg / 10ml. 50mg / 25ml. 200 mg / 100ml Injection
PDF Leaflet Revision Date: 07 December 2012
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of various cancers including breast and lung cancer.
Dosage (summary)
60-90 mg/mu00b2 IV every 3-4 weeks; adjust for hepatic/renal impairment.
Special Populations
- Elderly
- Hepatic impairment
- Renal impairment
Pregnancy & Breastfeeding
Contraindicated in pregnancy; may cause amenorrhoea in women and chromosomal damage in sperm.
Key Drug Interactions
- Cimetidine increases AUC by 50%
- Additive toxicity with other cytotoxic agents
Contraindications
- Hypersensitivity
- Severe hepatic impairment
- Severe myocardial insufficiency
- Persistent myelosuppression
Common side effects
- Leukopenia
- Neutropenia
- Anaemia
- Congestive heart failure
- Nausea
- Vomiting
Counselling Points
- Monitor blood counts regularly
- Avoid live vaccines
- Use effective contraception during treatment
Serious warnings
- Severe local tissue necrosis on extravasation
- Risk of cardiotoxicity
- Secondary acute myelogenous leukaemia
Important Disclaimer
The Farmorubicin 10mg / 5ml. 20mg / 10ml. 50mg / 25ml. 200 mg / 100ml Injection professional information leaflet below is the property of Pfizer and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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