Decasone Forte 100mg/5ml Injection
Clinical Summary
Quick overview from the medicine insert
Indication
Adjunctive treatment of severe shock.
Dosage (summary)
1.66-5 mg/kg IV, may repeat every 2-6 hours for up to 72 hours.
Onset of Action / Duration
Onset: Rapid, Duration: Biological half-life ~190 mins.
Special Populations
- Elderly
- Renal impairment
- Diabetes mellitus
- Hypertension
Pregnancy & Breastfeeding
Caution in pregnancy; may cause fetal adrenal suppression.
Key Drug Interactions
- Barbiturates
- Carbamazepine
- Phenytoin
- NSAIDs
Contraindications
- Hypersensitivity to corticosteroids
- Peptic ulcer
- Osteoporosis
- Acute infections
Common side effects
- Oedema
- Hypertension
- Hyperglycaemia
- Delayed wound healing
Counselling Points
- Monitor for signs of infection
- Gradual withdrawal recommended
- Avoid live vaccines during treatment
Serious warnings
- Risk of infection
- Cardiovascular collapse with rapid IV administration
- Adrenal insufficiency on withdrawal
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