Dytorez 10/10 ,10/20, 10/40 & 10/80 10 mg, 20 mg, 40 mg & 80 mg Tablet
PDF Leaflet Revision Date: 24 January 2023
Clinical Summary
Quick overview from the medicine insert
Indication
Adjunctive therapy for primary and homozygous familial hypercholesterolaemia.
Dosage (summary)
Starting dose: 10/10 mg once daily; max dose varies by indication.
Onset of Action / Duration
Onset: 2 weeks, Duration: 4 weeks for max response.
Special Populations
- Elderly
- Hepatic impairment
- Renal impairment
Pregnancy & Breastfeeding
Contraindicated in pregnancy and lactation; no data on excretion in breast milk.
Key Drug Interactions
- CYP3A4 inhibitors
- Warfarin
- Fibrates
- Ciclosporin
Contraindications
- Hypersensitivity
- Pregnancy
- Lactation
- Moderate to severe hepatic impairment
Common side effects
- Myopathy
- Rhabdomyolysis
- Increased transaminases
- Abdominal pain
- Fatigue
Counselling Points
- Monitor for muscle pain
- Avoid grapefruit juice
- Use contraception in women of childbearing age
Serious warnings
- Liver effects
- Myopathy risk
- Haemorrhagic stroke risk
Important Disclaimer
The Dytorez 10/10 ,10/20, 10/40 & 10/80 10 mg, 20 mg, 40 mg & 80 mg Tablet professional information leaflet below is the property of Pharma Dynamics and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
Healthcare Professionals Only
This content is for registered healthcare professionals
Sign in or create a free account to read the full package insert.
Free for HPCSA-registered professionals. Powered by Medinsert.
