Detryp 10/ 25/ 50 Mg 10 mg, 25 mg, 50 mg Tablets
PDF Leaflet Revision Date: 06 December 2022
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of endogenous depression and nocturnal enuresis in children over 6 years.
Dosage (summary)
Depression: Initial 25 mg TID, max 150 mg daily. Enuresis: 10-20 mg at bedtime for children 6-10 years; 25-50 mg for 11-16 years.
Onset of Action / Duration
Onset: 3-4 days, Duration: up to 30 days for full effect.
Special Populations
- Elderly
- Renal impairment
- Hepatic impairment
Pregnancy & Breastfeeding
Not recommended during pregnancy or breastfeeding due to potential risks.
Key Drug Interactions
- MAOIs
- CNS depressants
- Antihypertensives
Contraindications
- Hypersensitivity
- Acute myocardial infarction
- Heart block
- Severe liver disease
- Pregnancy
- Lactation
Common side effects
- Dry mouth
- Constipation
- Drowsiness
- Tachycardia
Counselling Points
- Avoid alcohol
- Do not drive until effects are known
- Monitor for mood changes
Serious warnings
- Risk of suicidal thoughts
- Cardiac dysrhythmias
- Severe anticholinergic effects
Important Disclaimer
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