Dynator Plus 10/10 Mg, 10/20 Mg, 10/40 Mg & 10/80 Mg 10 mg, 20 mg, 40 mg & 80 mg Tablet
PDF Leaflet Revision Date: 05 March 2025
Clinical Summary
Quick overview from the medicine insert
Indication
Adjunctive therapy for primary hypercholesterolaemia and homozygous familial hypercholesterolaemia.
Dosage (summary)
Starting dose is 10/10 mg once daily; adjust based on LDL-C levels.
Onset of Action / Duration
Onset: 2 weeks, Duration: 4 weeks for maximum response.
Special Populations
- Elderly
- Hepatic impairment
- Renal impairment
Pregnancy & Breastfeeding
Contraindicated in pregnancy and lactation; no data on excretion in breast milk.
Key Drug Interactions
- CYP3A4 inhibitors
- Warfarin
- Fibrates
- Ciclosporin
- Grapefruit juice
Contraindications
- Hypersensitivity to components
- Pregnancy
- Lactation
- Moderate to severe hepatic impairment
- Active liver disease
Common side effects
- Myopathy
- Rhabdomyolysis
- Increased transaminases
- Headache
- Fatigue
Counselling Points
- Take with or without food
- Report muscle pain or weakness
- Use effective contraception in women of childbearing age
Serious warnings
- Risk of liver injury
- Risk of myopathy
- Monitor liver function tests
Important Disclaimer
The Dynator Plus 10/10 Mg, 10/20 Mg, 10/40 Mg & 10/80 Mg 10 mg, 20 mg, 40 mg & 80 mg Tablet professional information leaflet below is the property of Pharma Dynamics and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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